Biomedical Photonics Handbook, Volume 3: Therapeutics and by Tuan Vo-Dinh

By Tuan Vo-Dinh

Formed by way of Quantum conception, know-how, and the Genomics Revolution

The integration of photonics, electronics, biomaterials, and nanotechnology holds nice promise for the way forward for medication. This subject has lately skilled an explosive progress as a result of the noninvasive or minimally invasive nature and the cost-effectiveness of photonic modalities in clinical diagnostics and treatment. the second one version of the Biomedical Photonics guide offers contemporary primary advancements in addition to vital purposes of biomedical photonics of curiosity to scientists, engineers, brands, lecturers, scholars, and scientific companies. the 1st quantity, basics, units, and strategies, makes a speciality of the basics of biophotonics, optical ideas, and devices.

Represents the Collective paintings of over a hundred and fifty Scientists, Engineers, and Clinicians

Designed to demonstrate the latest advances in instrumentation and strategies, in addition to medical purposes in vital parts of biomedical photonics to a wide viewers, this three-volume instruction manual offers an inclusive discussion board that serves as an authoritative reference resource for a huge viewers interested in the study, educating, studying, and perform of clinical technologies.

What’s New during this Edition:

A big choice of photonic biochemical sensing applied sciences has already been constructed for scientific tracking of physiological parameters, resembling blood strain, blood chemistry, pH, temperature, and the presence of pathological organisms or biochemical species of scientific significance. complex photonic detection applied sciences integrating the most recent wisdom of genomics, proteomics, and metabolomics permit sensing of early affliction states, therefore revolutionizing the drugs of the long run. Nanobiotechnology has opened new probabilities for detection of biomarkers of sickness, imaging unmarried molecules, and in situ diagnostics on the single-cell point. as well as those state of the art developments, the second one version comprises new themes and chapters including:

• Fiber Optic Probe Design

• Laser and Optical Radiation Safety

• Photothermal Detection

• Multidimensional Fluorescence Imaging

• floor Plasmon Resonance Imaging

• Molecular distinction Optical Coherence Tomography

• Multiscale Photoacoustics

• Polarized gentle for scientific Diagnostics

• Quantitative Diffuse Reflectance Imaging

• Interferometric mild Scattering

• Nonlinear Interferometric Vibrational Imaging

• Multimodality Theranostics Nanoplatforms

• Nanoscintillator-Based Therapy

• SERS Molecular Sentinel Nanoprobes

• Plasmonic Coupling Interference Nanoprobes

Comprised of 3 books: quantity I: basics, units, and strategies; quantity II: Biomedical Diagnostics; and quantity III: Therapeutics and complex Biophotonics, this moment version comprises 8 sections, and gives introductory fabric in every one bankruptcy. additionally it is an summary of the subject, an intensive selection of spectroscopic facts, and lists of references for additional reading.

Table of Contents - quantity Three:

Therapeutic and Interventional Techniques

Mechanistic rules of Photodynamic remedy; Barbara W Henderson Sandra O Gollnick

Synthesis and organic importance of Porphyrin-based Photosensitizers in Photodynamic remedy; Penny Joshi Ravindra ok Pandey

Lasers in Dermatology; Lilit Garibyan H Ray Jalian Kittisak Suthamjariya and R Rox Anderson

Lasers in Interventional Pulmonolog; Anubhav N Mathur Praveen N Mathur

Lasers in Diagnostics and remedy of mind affliction; Steen J Madsen Bernard Choi Henry Hirschberg

Lasers in Ophthalmology; Ezra Maguen Thomas G Chu and David Boyer

Lasers in Otolaryngology; Lou Reinisch

Therapeutic purposes of Lasers in Gastroenterology; Masoud Panjehpour Bergein F Overholt

Low-Power Laser treatment; Tina I Karu

Image Guided surgical procedure; Richard D Bucholz Keith A Laycock

Optical tools for Caries Detection prognosis and healing Intervention; Daniel Fried

Nonlinear Interferometric Vibrational Imaging and Spectroscopy; Haohua Tu Zhi Jiang Praveen D Chowdary Wladimir Benalcazar Eric J Chaney Daniel L Marks Martin Gruebele Stephen A Boppart

Multifunctional Theranostic Platform: Plasmonic-Active Gold Nanostars; Hsiangkuo Yuan, Andrew M Fales, Tuan Vo-Dinh

Activity Of Psoralen-Functionalized Nanoscintillators opposed to melanoma Cells Upon X-Ray Excitation; John Scaffidi Molly ok Gregas Bernard Lauly Yang Zhang Tuan Vo-Dinh

Advanced Biophotonics and Nanophotonics

Living telephone research utilizing Optical equipment; Pierre M Viallet Tuan Vo-Dinh

Amplification innovations for Optical Detection; man D Griffin Dimitra N Stratis-Cullum Timothy E McKnight M Wendy Williams Tuan Vo-Dinh

Fluorescent Probes in Biomedical program; Darryl J Bornhop Kai Licha and Lynn E Samuelson

Optical Trapping strategies in Bioanalysis; Kenji Yasuda

Luminescent Nanoparticle-Based Probes for Bioassays; Georgeta Crivat Sandra M Da Silva Ashley D Quach Venkata R Kethineedi Matthew A Tarr and Zeev Rosenzweig

Fluorescent Molecular Beacon Nucleic Acid Probes for Biomolecular attractiveness; Cuichen Wu Chaoyong James Yang Kemin Wang Xiaohong Fang Terry Beck Richard Hogrefe Weihong Tan

Luminescent Quantum Dots for Diagnositc and Bioimaging purposes; Brad A Kairdolf Shuming Nie

PEBBLE Nanosensors for In Vitro Bioanalysis; Yong-Eun Koo Lee Eric Monson Murphy Brasuel Martin A Philbert Raoul Kopelman

Nanosensors for Single-Cell Analyses; Charles ok Klutse Brian M Cullum, Molly ok Gregas, John P Scaffidi, Tuan Vo-Dinh

SERS Molecular Sentinel Nanoprobes to notice Biomarkers for scientific Diagnostics; Tuan Vo-Dinh Hsin-Neng Wang Hoan Thanh Ngo

Plasmonic Coupling Interference (PCI) Nanoprobes for Gene Diagnostics; Hsin-Neng Wang Stephen Norton Tuan Vo-Dinh

DNA Sequencing utilizing Fluorescence Detection; Steven A Soper, Clyde V Owens, Suzanne J Lassiter, Yichuan Xu and Emanuel Waddell

In Vivo Bioluminescence Imaging as a device for Drug improvement; Pamela R Contag Christopher H Contag

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Additional resources for Biomedical Photonics Handbook, Volume 3: Therapeutics and Advanced Biophotonics (2nd Edition)

Example text

214 Taken together, PDT creates a tumor milieu that is conducive to the antitumor immune modulation215 that has been documented in both preclinical and clinical studies. 217 have shown that PDT-treated mice that remain tumor free for 100 days post-PDT are resistant to subsequent tumor challenges, suggesting the presence of immune memory cells. 197,209 PDT treatment, at a dose that was curative in immunocompetent BALB/c mice, provided only short-term cures of EMT6 tumors in SCID and nude mice. The ability to provide long-term cures was restored when immunodeficient animals were reconstituted with bone marrow cells from BALB/c mice.

Henkel T. Apoptosis: Corralling the corpses. Cell 2001;104:325–328. 46. Agostinis P, Berg K, Cengel KA, Foster TH, Girotti AW, Gollnick SO et al. Photodynamic therapy of cancer: An update. CA Cancer J Clin 2011;61:250–281. , Agostinis P, Berg K, Oleinick NL, Kessel D. Assessing autophagy in the context of photodynamic therapy. Autophagy 2010;6:7–18. 20 Biomedical Photonics Handbook: Therapeutics and Advanced Biophotonics 48. Dewaele M, Maes H, Agostinis P. ROS-mediated mechanisms of autophagy stimulation and their relevance in cancer therapy.

79. Luna MC, Ferrario A, Wong S, Fisher AMR, Gomer CJ. Photodynamic therapy-mediated oxidative stress as a molecular switch for the temporal expression of genes ligated to the human heat shock promoter. Cancer Res 2000;60:1637–1644. 80. Gomer CJ, Ryter SW, Ferrario A, Rucker N, Wong S, Fisher AMR. Photodynamic therapy-mediated oxidative stress can induce expression of heat shock proteins. Cancer Res 1996;56:2355–2360. 81. Curry PM, Levy JG. Stress protein expression in murine tumor cells following photodynamic therapy with benzoporphyrin derivative.

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