Biological Research on Addiction: Comprehensive Addictive by Peter M. Miller

By Peter M. Miller

Biological study on Addiction examines the neurobiological mechanisms of drug use and drug dependancy, describing how the mind responds to addictive elements in addition to the way it is plagued by medicines of abuse. The book's 4 major sections study behavioral and molecular biology; neuroscience; genetics; and neuroimaging and neuropharmacology as they relate to the addictive process.

This quantity is mainly potent in providing present wisdom at the key neurobiological and genetic components in an individual’s susceptibility to drug dependence, in addition to the tactics wherein a few participants continue from informal drug use to drug dependence.

Biological learn on Addiction is one in every of 3 volumes comprising the 2,500-page sequence, Comprehensive Addictive Behaviors and Disorders. This sequence presents the main whole number of present wisdom on addictive behaviors and problems thus far. briefly, it's the definitive reference paintings on addictions.

  • Each article presents word list, complete references, advised readings, and a listing of internet resources
  • Edited and authored through the leaders within the box around the world – the broadest, such a lot specialist assurance available
  • Discusses the genetic foundation of addiction
  • Covers uncomplicated technology learn from a number of animal studies

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Extra info for Biological Research on Addiction: Comprehensive Addictive Behaviors and Disorders, Volume 2

Sample text

Increased pulse rate or sweating) Nausea/vomiting Transient visual, tactile, or auditory hallucinations Psychomotor agitation Grand mal seizures Persons that meet criteria for alcohol dependence can be further grouped as follows: a. With physiological dependence; evidence of tolerance or withdrawal b. Without physiological dependence; no evidence of tolerance or withdrawal (NIAAA) has defined “heavy drinking” as five or more drinks per day for men and four or more drinks per day for women. 9 million Americans are heavy drinkers, consuming five or more alcoholic beverages per day, five or more times per month.

The primary advantage of self-dosing is that it models human “heavy drinking” in a manner that produces high levels of alcohol intake that are initiated and maintained by the animal. In addition, although high levels of intake are achieved via selfdosing, animals remain healthy and extreme weight loss and severe withdrawal symptoms (seizures and death) are not observed. g. ) are being investigated. Alcohol Seeking and Relapse Current theories for addiction propose a transitional shift in associative learning processes whereby alcohol seeking is a conditioned response habit triggered and I.

Behavioral Neuroscience 125 (2), 184–193. , 2008. Vapor inhalation of alcohol in rats. 29 (suppl. 19. , 2001. Behavioral sensitization to ethanol in rats: evidence from the Sprague-Dawley strain. Pharmacology Biochemistry and Behavior 68 (4), 685–690. , 2010. Animal models of substance abuse and addiction: implications for science, animal welfare, and society. Comparative Medicine 60 (3), 177–188. I. , 2011. Fluoxetine, Desipramine and the dual antidepressant milnacipran reduce alcohol self-administration and/or relapse in dependent rats.

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